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Among Chicago’s many blues clubs, B.L.U.E.S feels the most like a Southern juke joint. Chalk it up to the narrow confines, loud sounds, and sweaty dancers. The club is across the street from the popular Kingston Mines, but it’s a better choice for older, more musically versed blues fans. Better yet, why not stop into both!

With the chain’s signature wrap-around bar and bright mosaics, this bar is a comfortable favorite for young professionals who appreciate the moderately priced drinks, plenty of tap beers, and huge sandwiches.

One of several popular Bar Louies in town, this Little Italy outpost plies generous martinis (and great bar food) to a twenty-something crowd.

For 20 years, this edgy club has attracted every type from straight girls to drag queens. After midnight, the dance floor hits its peak, rocking with a stellar sound system and light show.

This dark, intimate Little Italy hideaway is a great place to cozy as a couple before or after dinner with one of 40 by-the-glass wines, or a “sampling flight” of three wines.

You don’t have to be a beauty school grad to let your hair down at this off-the-beaten-track dance club: in fact, helmet-style hair dryers serving as hanging lights are the only reference to the cute name. A varied crowd packs the neon-lit dancefloor, while local DJs spin techno, house, and hip-hop. Distortion Sundays feature punk and indie music, as well as cult and Kung Fu videos.

A wine bar of warehouse proportions, Bin 36 engenders an infectious enthusiasm for wine and food. The many small dishes encourage sampling.

Popular with tourists, Blue Chicago in River North operates two clubs located two blocks apart. Seats at both venues are few and far between, so come early if you need one, or be prepared to dance. The Admission charge covers both clubs, which encourages bar hopping.