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Featuring artists of critical acclaim in several media.

Anchored by Macy’s, which opened in 1858, this was once a popular district known as “Fashion Row”. The 1876 cast-iron façade of the Hugh O’Neill Dry Goods Store at Nos. 655–71 exemplifies the era, when the arrival of the 6th Avenue elevated line provided easy access to the area. As Manhattan’s commercial center moved northward, these cast-iron palaces were left deserted until recently, when they found new life as bargain fashion outlets and superstores.

Since moving from SoHo to Chelsea, Rosen’s eclectic shows have made this one of the area’s most visited galleries.

On weekends, year-round, an empty parking lot becomes one of the city’s most popular outdoor markets. A tradition for more than 30 years, some 600 dealers, from Maine to Maryland, set up booths selling clothing, silver, jewelry, furniture, art, and “junktiques” from old tools to vintage eyeglasses. Many prize antiques can be discovered at The Amex, an indoor market just around the corner at 112 West 25th Street, and at The Showplace, 40 West 26th Street, with 135 dealers on three floors.

A dramatic backdrop for large-scale pieces, video pioneers, and photography.

Thanks to the booming gallery scene, this attracts a stylish crowd for good northern Italian fare and a lovely garden.

A romantic bit of Paris in Chelsea, with a candlelit terrace and sophisticated bistro menu.

Clement Moore, author of A Visit from St. Nicholas , developed this land in the 1830s. The finest of the townhouses built here are the seven known as “Cushman Row,” Nos. 406–18 West 20th Street, which are among the city’s best examples of Greek Revival architecture. Houses at Nos. 446–50 West 20th are in the Italianate style, for which Chelsea is also known.

Seedy it is, yet there’s a definite mystique to this 1884 building bedecked with wrought-iron balconies. Once a fancy apartment, it became a hotel favored by musicians, artists, and writers. Former guests, commemorated on brass plaques outside, include Tennessee Williams, Mark Twain, Jack Kerouac, and Brendan Behan. Dylan Thomas spent his last years here. Notoriously, it was also the place where punk rocker Sid Vicious killed his girlfriend Nancy Spungeon in 1978. Step into the lobby and take a look at the wild artwork, and soak up the ambience at the bar.