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The mammoth museum whose holdings include 32 million artifacts.

This 1908 apartment-hotel included soundproof partitions, a feature that has attracted many distinguished musicians.

Modeled after an Italian Renaissance palazzo, this luxury 1908 building includes a huge interior courtyard.

Even larger than the Apthorp, this 1908 Renaissance Revival structure is where Nobel Prize-winning author Isaac Bashevis Singer lived and wrote.

A classic Parisian bistro with a zinc-topped bar and a hip clientele. The steak frites can’t be beat.

Every night feels like a Latin party here; modern dishes from the Cuban chef are inspired by cuisine from Peru to Puerto Rico.

Irwin Chanin’s second twin tower, the tallest on the block, and an Art Deco icon.

Founded in 1973, in a former school building, this is a museum dedicated to the principal that children learn best through self-discovery. It uses a variety of participatory activities and fantasy world environments to engage its young visitors in learning that is fun. The Tisch Building, as the museum is known, has been renovated in a $6.5 million expansion headed by the museum chairman, Laurie Tisch Sussman. The museum’s many activities include exhibits to intrigue older children, while Word Play is an enticing environment for newborns to four year olds.

One of the largest building projects in New York’s history is transforming this neglected urban plaza into an important public site. The redevelopment has attracted national and international businesses, such as giant media company Time Warner, which now has its headquarters in an 80-storey skyscraper. The new building contains shops, entertainment, restaurants, and the Mandarin Oriental hotel. It is also the new home of Jazz at the Lincoln Center, the world’s first performing arts facility dedicated to jazz. Other buildings in Columbus Circle include Hearst House, Trump International Hotel, and the Maine Monument.

Famous as the site where John Lennon was shot, the block was thought so far west in 1884, it might as well be in Dakota.