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This larger-than-life, 700-year-old statue of the Virgin and Child is the Czech National Gallery’s most prized possession. The gestures of the Madonna are strikingly rigid, and evoke the Classical French sculpture found in places such as Reims Cathedral.

Bohemia’s most celebrated Marian painting is evocative of Byzantine icons in its style. The ring on the Madonna’s left-hand finger symbolizes the Church through the mystical marriage between Christ and the Virgin Mary. The work has been moved to St Agnes’s Convent from a Cistercian monastery where the majority of the Přemyslid kings were laid to rest.

The 14th-century cycle begins with the Annunciation , then proceeds through the Adoration of the Magi to Pentecost . The creator of these beautiful panels is unknown.

Parts of an altar set on loan from Karlštejn Castle, are St Luke , St Charlemagne , St Catherine , St Matthew , St Ambrose and St Gregory .

Only three of the five double-sided panels of the 14th-century Třebon Altar-piece have survived to the present day.

The origin of these 14 panels is unknown. The Virgin Mary is flanked by St Peter on the left and Christ on the right.

Originating in south Bohemia around 1500, this is a rare example of a completely preserved altar. Beneath the Madonna, cherubs hold the vera icon.

Albrecht Altdorfer created this painting as part of a multipanel altar featuring scenes from the legend of St Florian. Other pieces from the series are in Florence.

St Agnes gave up a life at court to pursue a spiritual vocation. She is typically depicted nursing the sick on this 15th-century altarpiece.

Although he’s considered the foremost German Renaissance artist, Albrecht Dürer is probably best known for woodcuts such as this series of 15 from 1498, which retain a strong Gothic flavour.